Autologous lung-derived mesenchymal stem cell transplantation in experimental emphysema.

Ingenito EP, Tsai L, Murthy S, Mazan MR, and Hoffman AM (2011).   Autologous lung mesenchymal stem cell transplantation in an emphysema model. Cell Transplant, Feb 3, ePub ahead of print; PMID 21294955.

Autologous lung-derived mesenchymal stem cells (LMSCs) were transplanted endoscopically into sheep with experimental emphysema to assess their capacity to regenerate functional tissue. LMSC lines were derived from transbronchial biopsies, cloned at passage 2, expanded in culture, and labeled.

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