Lung regeneration and translational implications of the postpneumonectomy model.

Thane K, Ingenito EP, and Hoffman AM. Invited Review: Lung regeneration and translational implications of the post-pneumonectomy model. Translational Research. 2014 Apr:163(4):363-76.


Lung regeneration research is yielding data with increasing translational value. The classical models of lung development, postnatal alveolarization, and postpneumonectomy alveolarization have contributed to a broader understanding of the cellular participants including stem-progenitor cells, cell-cell signaling pathways, and the roles of mechanical deformation and other physiologic factors that have the potential to be modulated in human and animal patients.

Read more at PubMed: http://www.ncbi.nlm.nih.gov/pubmed/24316173

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