Sarah Crain, MS, DACVIM (SAIM), PhD Candidate : She is examining the role of extracellular vesicles in immunomodulation by canine fetal (placental, umbilical cord matrix) mesenchymal stem cells. She is also conducting a dose-escalation clinical trial of allogeneic umbilical cord matrix (Wharton’ Jelly) derived mesenchymal stem cells for treatment of naturally occurring, refractory inflammatory bowel disease with protein-losing enteropathy (PLE) in dogs.
Our Most Recent Publications
- Regenerative cells in the ageing lung
- Treatment of perianal fistulas with human embryonic stem cell-derived MSCs: a canine model of human fistulizing Crohn’s disease.
- Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract-Induced Allergic Airway Inflammation in Immunocompetent Mice.
- Equine model for soft-tissue regeneration.
- Relationships between equine airway reactivity measured by flowmetric plethysmography and specific indicators of airway inflammation in horses with suspected inflammatory airway disease.